15 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... mucositis - Rash ... : • Behçet Syndrome ... central nervous system ... • Cogan Syndrome
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... Henoch-Schönlein purpura ... • Goodpasture syndrome ... #dermatology #rash
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Skin Rash on Physical ... shock, multiorgan system ... #Fulminans #Skin ... #Rash #clinical ... #photo
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... Mucocutaneous lymph node syndrome ... , mucositis • Rash ... • Behcet syndrome ... • Cogan syndrome
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Skin ulcers ... : • Clinical triad ... reticularis & skin ... disorder (e.g. systemic
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... or Vasculitis? ... later confirmed by skin ... #Legs #Rash #clinical ... #photo #dermatology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
(HSP, IgA Vasculitis ... ankles and palpable rash ... #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... , small-vessel vasculitis ... association • M > F Clinical ... lesions, palpable purpura ... (Clinical Dx).
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
air conditioning system ... +purpuric rash → ... purpura fulminans ... possible Patient's clinical ... #clinical #photo