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diagnosis rheumatology classification sle systemic vasculitis cryoglobulinemia dermatology differential drugrelated exanthema flexural hematology intertriginous macrophage management mas sdrife signs symmetrical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... : • Clinical triad ... reticularis & skin ... (e.g. systemic lupus ... erythematosus (
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... 3rd Decade Skin ... Clinical Features ... Seizures • Strokes Skin ... Chronic B-cell activation
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... Serologies for Cryoglobulins
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
groins/buttocks (pic ... well-demarcated, erythematous ... known as baboon syndrome ... , blisters, or purpura ... #clinical #photo
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