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diagnosis rheumatology dermatology differential signs symptoms classification management systemic activation behcet cryoglobulinemia cryoglobulins dermatologic disease drugrelated exanthema flexural gpa granulomatosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... Demyelinating syndromes ... #erythematosus #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... 3rd Decade Skin ... rash • Erythematous ... Clinical Features
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... , and SLE) • Urinalysis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... macules • Erythematous ... • Goodpasture syndrome ... #dermatology #rash
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... : • Clinical triad ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms ... Xeroderma (Dry skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... : Erythematous nodules ... , mucositis • Rash ... • Behcet syndrome ... • Cogan syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [ ... SLE], AOSD) • Infection
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, palpable purpura ... (Clinical Dx). ... Oral aphthae : SLE ... • Arthritis: SLE
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