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diagnosis rheumatology differential dermatology classification sle systemic algorithm causes clinical cryoglobulinemia cryoglobulins dermatologic drugrelated exanthema flexural granulomatosis hematology intertriginous joint
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome ... #dermatology #rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... • ANCA (Dx: GPA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... reticularis & skin ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... erythematosus (
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... : - Purpura fulminans ... (lupus, RA, Sjogren's ... , GPA, EGPA, Microscopic ... cryoglobulins • Skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... SLE #systemic #erythematosus
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... MPO > PR3 60/ GPA ... • Behcet syndrome ... • Cogan syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Autoimmunity: • -MM/WM: Vasculitis ... WAIHA • CAD • PCH ... to cold IgG • Lupus
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
groins/buttocks (pic ... well-demarcated, erythematous ... known as baboon syndrome ... , blisters, or purpura ... #clinical #photo
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