10 results
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Skin Rash on Physical ... shock, multiorgan system ... BIDMC Infectious Diseases ... #Fulminans #Skin ... #photo
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... mucositis - Rash ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... , such as systemic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... Mucocutaneous lymph node syndrome ... , mucositis • Rash ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... central nervous system ... nose (epistaxis), skin ... maculopapular rash ... vesicular rash,
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... lesions, palpable purpura ... response to local skin ... retinal damage) • Skin ... test (this is a skin
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
air conditioning system ... +purpuric rash → ... purpura fulminans ... University Infectious Diseases ... #clinical #photo
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Neuropsychiatric systemic ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
PALM RASHES 
Common features and patterns:
1.	Color:
o	Red or erythematous: Common in inflammatory or allergic reactions.
o	Purple or purpuric:
o Purple or purpuric ... occur in chronic skin ... , or bullous skin ... Fungal Infections (Tinea ... accompanied by systemic
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... Antisynthetase syndrome ... • Conduction system ... : • PBC, autoimmune