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diagnosis differential algorithm causes management clinical nephrology pharmacology treatment endocrinology pathophysiology cardiology secondary hematology table neurology workup comparison radiology primarycare
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
diagnostic of primary ... OR secondary AI ... suggests EITHER primary ... or secondary AI ... ACTH: - High = primary
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... Pathophysiology Primary ... AI = adrenal glands ... Secondary AI = the ... Medicine @ucsdim #Primary
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... Differentiate primary ... vs secondary AI ... consistent with primary
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Management Summary Primary ... In secondary AI ... diagnostic of AI ... diagnostic of AI ... Insufficiency #Primary
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... hypothyroidism - Primary ... AI present - ... IF < 18 ug/dL Primary ... AI present -
Hypophosphatemia - Measurement of urine phosphate excretion - Differential Diagnosis Algorithm • GI loss • Redistribution
Redistribution • Primary ... deficiency • Primary ... Hypophosphatemia #urine #urinary
Quincke's Pulse in Severe Aortic Regurgitation Little physical exam finding for the end of the week! Quinke’s
chronic severe AI ... associated with chronic AI
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 Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Idiopathic Eosinophilia Primary ... Eosinophilia: • Primary ... bartonella) • Rheum/AI
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
ACTH-Independent (Primary ... Insufficiency #AI
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
OBSTRUCTIVE • Urinary ... cervical cancer) • Urinary ... Glomerulonephritides (GN) • Primary ... Disease process primarily
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