14 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... purpura/hemolytic ... , Hematology 2012 ... #Differential # ... #Evaluation
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... #Differential # ... Diagnosis #hematology ... #nonpalpable #dermatology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... presents in thrombocytopenic ... require emergent evaluation ... palpable, the differential ... #Diagnosis #Dermatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... #Defects #comparison ... #table #differential ... #diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... Microangiopathy #thrombocytopenic ... #purpura #TTP # ... #Comparison #Diagnosis ... #Table #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... - Bone marrow evaluation ... #Differential # ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Findings in DIC: • Platelet ... - Platelet rich ... #Coagulation #diagnosis ... treatment #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
hemostasis: - Thrombocytopenia ... - Abnormal platelet ... Fever • Toxic appearance ... deficiency Work ... #Causes #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... for Thrombotic Thrombocytopenic ... Purpura Activity ... WBC count and differential ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... with or without platelet ... Schistocytes, thrombocytopenia ... #workup #hematology