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differential causes lymphadenopathy diffuse localized anemia gammopathies hemolytic leukemia mds mgus monoclonal multiplemyeloma myelodysplasia myelodysplastic petechiae physicalexam plasmacytoma polycythemia rash
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
- Differential Diagnosis ... Algorithm • Reactive ... ) #Diffuse #Focal ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... deficiency Work ... Urinalysis • Fecal ... #dermatology #physicalexam
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
- Differential Diagnosis ... Algorithm Cervical ... #Localized #Focal ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Reed-Sternberg Cells ... Lymphadenopathy #LAD ... #Hematology #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
marrow plasma cell ... ratio ≥100 • >1 focal ... , amyloidosis, solitary ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... cells - Consider ... sickle cell disease ... #Algorithm #workup ... #hematology #testing
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • T-cell ... activity • ↓ LAP ... Significant ↓ PLT: Petechiae ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... caused by bleeding (petechiae ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Better call hematology ... you’ll do a good workup ... #Algorithm #workup ... #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... Diagnosis? ... with improved local ... #Oncology #Diagnosis ... #Workup #Hematology
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