363 results
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
Antifibrinolytic Trial): tranexamic ... acid for the treatment ... controlled trial - Tranexamic ... acid may be beneficial ... consider giving tranexamic
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Multiple Uses for Tranexamic ... Acid (TXA) - Evidence
Nebulized Tranexamic Acid for acute treatment of stable hemoptysis 

- Mike O'Brien
@MikeEMPharmD

#Pharmacology #EBM #Management #Dosing #Pathophys
Nebulized Tranexamic ... Acid for acute
SGEM#210: (Don’t) Let it Bleed – TXA for Epistaxis in Patients on Anti-Platelet Drugs. Zahed et
Topical Tranexamic ... Acid Compared With
Woman – The TXA Trial for Post-Partum Hemorrhage.  Lancet. 2017 May 27
https://www.ncbi.nlm.nih.gov/pubmed/28456509

#EBM #OBGyn #WOMANTrial #TXA
Woman – The TXA Trial for Post-Partum Hemorrhage. Lancet. 2017 May 27 https://www.ncbi.nlm.nih.gov/pubmed/28456509 #EBM #OBGyn #WOMANTrial #TXA #TranexamicAcid #PostPartum #Hemorrhage #VisualAbstract
Survival Benefit Decreased by 10% for Every 15 min of Treatment Delay Until 3hr, After Which
Survival Benefit Decreased by 10% for Every 15 min of Treatment Delay Until 3hr, After Which There was no Benefit #EBM #Obstetrics #Trauma #TXA #TranexamicAcid #RebelEM
TXA: Effect of Treatment Delay on Survival #EBM #EM #OBGyn #Trauma #TXA #TranexamicAcid #RebelEM
TXA: Effect of Treatment Delay on Survival #EBM #EM #OBGyn #Trauma #TXA #TranexamicAcid #RebelEM
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... analog of the amino acid ... fibrin-rich clot #Tranexamic ... #Acid #pathophysiology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... disturbances #TXA #Tranexamic ... #Acid #Indications
Management of Anaphylaxis - Interventions
Epinephrine - Bolus, Infusion, Nebulized
Posture
O2
Fluids
Albuterol 
H1-Antihistamines, H2-Antihistamines
Glucocorticoids
Additional Vasopressor
Glucagon
Sugammadex
Methylene blue
Tranexamic acid
ECMO

#anaphylaxis #management #treatment
Methylene blue Tranexamic ... acid ECMO #anaphylaxis