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ED Treatment of Abnormal Uterine Bleeding Hemodynamically unstable Resuscitation • ABCs! • Fluids +
pregnancy related cause ... 25mg Q4-6H • Transexamic ... acid (PO or [V)
Tranexamic Acid: Mechanism of Action - TXA is an anti-fibrinolytic - TXA is a synthetic analog
Tranexamic Acid: ... analog of the amino acid ... fibrin-rich clot #Tranexamic ... #Acid #pathophysiology
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... : Urine Common Uses ... rapid injection; Nausea ... disturbances #TXA #Tranexamic ... #Acid #Indications
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing Trauma < 3 hrs •
Multiple Uses for ... Tranexamic Acid
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
Antifibrinolytic Trial): tranexamic ... acid for the treatment ... controlled trial - Tranexamic ... acid may be beneficial ... consider giving tranexamic
Management of Anaphylaxis - Interventions Epinephrine - Bolus, Infusion, Nebulized Posture O2 Fluids Albuterol H1-Antihistamines, H2-Antihistamines Glucocorticoids Additional Vasopressor Glucagon Sugammadex Methylene blue Tranexamic acid ECMO #anaphylaxis #management #treatment
Methylene blue Tranexamic ... acid ECMO #anaphylaxis
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
increased -> 1000mg tranexamic ... acid - Dr.
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
increased -> 1000mg tranexamic ... acid Dr.
High Anion Gap Metabolic Acidosis (HAGMA) - Mnemonics Why should we switch from MUDPILES to GOLDMARK? •
toxins that can cause ... Three new organic acids ... and acid precursors ... recognized as causes
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
to filter uric acid ... like lactic acid ... and keto-acids) ... secretion of uric acid ... Release of purine bases
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