892 results
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... Mechanism of Action - TXA ... anti-fibrinolytic - TXA ... acid lysine - TXA ... fibrin-rich clot #Tranexamic
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Multiple Uses for Tranexamic ... Acid (TXA) - Evidence ... Hemoptysis YES #TXA
Indications for tPA in Stroke:
 • Clinical diagnosis of ischemic stroke
 • Measurable neurologic deficit
 •
Indications for tPA ... in Stroke: • ... to intravenous tPA ... Contraindications to tPA ... #Indications #tPA
Blood Pressure Management for Neurologic Emergencies
 - SAH 
 - ICH 
 - TBI 
 -
TBI - Ischemic Stroke ... (no TPA) - Ischemic ... Stroke + TPA By ... #Targets #CVA #Stroke
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... disturbances #TXA ... #Tranexamic #Acid
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
Antifibrinolytic Trial): tranexamic ... controlled trial - Tranexamic ... consider giving tranexamic ... Obgyn #WOMANTrial #TXA
Hypertensive Emergency and Hypertensive Crisis - Blood Pressure Targets
 • Hypertensive Emergency
 • Ischemic Stroke (w/
Emergency • Ischemic Stroke ... (w/ tPA, w/o tPA ... • Hemorrhagic Stroke
Restarting Anticoagulation after TIA or Acute Ischemic Stroke

 • TIA → Consider (re-) starting a NOAC
Anticoagulation after TIA ... Acute Ischemic Stroke ... • TIA → Consider ... ≥ 1 day after stroke ... Anticoagulation #TIA
Blood pressure management in acute ischemic stroke - Timeline
Candidate for tPA:
 - Goal SBP <185 AND
acute ischemic stroke ... Candidate for tPA ... Candidate for tPA ... Hypertension #CVA #Stroke
Ischemic Stroke - Blood Pressure Management
 • No tPA  < 220 / 120 (permissive hypertension)
Ischemic Stroke ... Management • No tPA ... hypertension) • tPA ... SCVMCMed #Ischemic #Stroke