22 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... (Drug-induced liver ... Diagnosis #hepatology #transaminitis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... Trauma: Shock liver ... • Autoimmune hepatitis ... images/10587 #Transaminitis ... Transaminases #hepatitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... - Acute Viral Hepatitis ... , Toxic Hepatitis ... #Patterns #Liver ... hepatology #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... • Infections: Hepatitis ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... differential #Hepatology #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HAV immunity; Liver ... elastographv, liver ... • Liver is the ... Diagnosis #Management #Treatment
Interstitial keratitis in Tertiary Syphilis

Interstitial keratitis, which is an inflammation of the cornea’s connective tissue elements,
Interstitial keratitis ... Interstitial keratitis ... Without treatment ... blood vessels, liver ... syphilis #clinical #photo
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... infection with severe liver ... mg/dL) or acute liver ... failure #HepatitisB
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... Alcohol-related liver ... ascites), Chronic hepatitis ... • Autoimmune hepatitis