6 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • AST/ALT elevation ... • R value = (ALT ... #Cholestatic #Transaminitis ... #diagnosis #differential
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... ALP ≥ 2x ULN R Value ... ALP) ≥5: Hepatocellular ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... muscle, Kidneys • LDH ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Hepatocellular ... Burak @kwburak #LFTs ... #Elevated #Abnormal
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
) - Differential ... RBCs, muscle, liver ... hepatitis • Acute Hepatocellular ... Elevation: • ... #differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... specificity to elevated ... Bilirubin - +/- elevation ... Enzyme Elevation ... muscle, kidneys • LDH