5 results
diagnosis hepatology differential management acute algorithm chemistry chronic cirrhosis failure function functiontest idiosyncratic induced interpretation rvalue tests
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #Drug #induced ... #Liver #Injury #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... Diagnosis #hepatology #transaminitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... abnormality vs bone Bili ... Hepatocellular injury ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) ... Guidelines ACLF ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Cirrhosis #Hepatology #gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Failure (ALF): ... • Liver injury ... differential #Hepatology #transaminitis ... #LFTs #RValue #
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