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diagnosis purpura causes rash hematology algorithm petechial rheumatology vasculitis anemia arterial blanching bruise clinical coagulation ddxof dermatologic dic disseminated ecchymosis
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
with devastating differential ... , the differential ... , disseminated intravascular ... #Diagnosis #Dermatology ... #Differential
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... erythrocytes from the intravascular ... vascular integrity (trauma ... #Diagnosis #Dermatology ... #Algorithm #Differential
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura - Differential ... Thrombocytopenia ... warfarin necrosis), Trauma ... BrighamChiefs #Purpura #nonpalpable ... #Differential #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... hemostasis: - Thrombocytopenia ... integrity: - Trauma ... #Differential # ... Algorithm #Causes #dermatology
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Integrity: • Trauma ... Primary hemostasis: Thrombocytopenia ... BrighamChiefs #Purpura #nonpalpable ... #palpable #Causes ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... • Mechanical Trauma ... microangiopathy: Thrombotic thrombocytopenic ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... Solar purpura - Trauma ... #nonpalpable #dermatology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
non-blanching, nonpalpable ... vasculitis is usually palpable ... individuals with thrombocytopenia ... of blood in the extravascular ... VWF:RCo/VWF:Ag (differentiate
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Recent history of trauma ... Manifestations of DIC: • Petechiae ... • Purpura • Palpable ... #Disseminated #Intravascular
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... reticularis Differential
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