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diagnosis differential eosinophilia hes hypereosinophilia oncology treatment allergy anemia aplastic cerebritis classification cns common cryoglobulinemia cryoglobulins cvid disorders eosinophil erythematosus
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Secondary ... and Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Diagnosis and Management ... Secondary Causes ... #diagnosis #hematology ... #differential #management
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... causes of eosinophilia ... (common causes ... Differential #diagnosis #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... ESRD & CAD • Eosinophilic ... cell activation syndrome ... Differential #Diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... APS), Secondary ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... ) Meltzer's Triad ... Type III Often Secondary ... classification #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... lung disease Caused ... 10 minutes of rest ... hepatopulmonary #syndrome ... #treatment #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology
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