15 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... Causes of pathologic ... Diagnosis #Peds #Pediatrics ... #Algorithm #Differential ... #Workup #bilirubinemia
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Cholangitis #Jaundice ... #Differential # ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... Diagnosis and Workup ... #Differential # ... #Workup #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... malaise, are common Crigler-Najjar ... and stress may cause ... Congenital #bilirubin #hepatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... 1,500 cells/µL Workup ... #Algorithm #Differential ... #diagnosis #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... Alzheimer - 1st cause ... Dementia - 2nd cause ... MNCD #Dementia #Differential ... #Diagnosis #Geriatrics
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... #hepatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... tendency to fall • Triggers ... antibody that works ... limb or joint disorders
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... formed or don’t work ... Workup: • Complete ... blood count with differential