8 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... Causes of pathologic ... #Diagnosis #Peds ... #Algorithm #Differential ... #Workup #bilirubinemia
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #Causes #Hepatology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
drugs, biliary cirrhosis ... miscellaneous causes ... Classification #diagnosis ... #unconjugated #differential ... #causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... #workup #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
Diagnosis The ... most common causes ... more than one cause ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral ... Liver #Pregnancy #hepatology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... arteriovenous shunting causes ... • Stigmata of cirrhosis ... : jaundice, ascites ... #diagnosis #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Causes of Monoclonal ... Liver disease: Cirrhosis ... Gap #ProteinGap #differential ... #diagnosis #hematology