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biliary iem inbornerrors lfts liver metabolism neonatology nicu patterns pbc pediatrics primary transaminitis albumin algorithm apml ascites causes cholangitis comparison
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... Smoking, Microbial triggers ... DNA methylation Genetic ... Primary #Biliary #Cirrhosis ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Methotrexate Genetic ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
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 A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
the lab values table ... MetabolicEmergency #Genetics ... #Diagnosis #Algorithm ... #Differential # ... Neonatology #Peds
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
Metabolism A table ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Neonatology #Peds ... #Pediatrics #Table ... #NICU #Genetics
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG) SAAG ≥ 1.1: • Cirrhosis • Portal
Ascites Differential ... Diagnosis Table ... SAAG ≥ 1.1: • Cirrhosis ... #Diagnosis #Table ... Gradient #SAAG #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Diagnosis Framework ... • NAFLD • Cirrhosis ... 500-1000): • Genetic ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
CMV), Alcoholic cirrhosis ... Hemolysis, NASH, Genetic ... Liver #Injury #hepatology ... transaminitis #differential ... #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... bile ducts Differential ... Diagnosis: • ... #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
serotoninergic meds ... disease caused by genetic ... ryanodine receptor) & triggered ... Toxidromes #comparison #table ... #diagnosis #differential
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