17 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... = nonspecific (nausea ... infiltration) Differential ... #Pregnancy #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... Trauma: Shock liver ... • Metabolic: ... #Diagnosis #causes ... #hepatology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... and decreased metabolism ... Reye syndrome (Peds ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... • Metabolic/Hereditary ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Syndrome, Ischemic Liver ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
other obvious causes ... through reduced cGMP metabolism ... hemodynamics Liver ... Hypertension #diagnosis #management ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology