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diagnosis cirrhosis hyperbilirubinemia inherited management syndrome 21hydroxylasedeficiency 21ohd abscess aflp algorithm apml biliary bilirubin cardiology causes childhood children cholangitis differentiation
Congenital Long QT Syndrome: Illness Script Who? - Kids or young adults, usually < 30 - high
Congenital Long ... prevalence - 1/2000 live ... births Symptoms ... arrest/death - Symptoms ... term monitor** Triggers
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Clinical features of Liver Disease in Children #Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings #Diagnosis #Peds #Pediatrics #Hepatology **
Clinical features of Liver ... LiverFailure #Signs #Symptoms ... Findings #Diagnosis #Peds ... #Pediatrics #Hepatology
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
Unconjugated Crigler-Najjar ... Hyperbilirubinemia #pathophysiology ... #congenital #hepatology ... #pediatrics #peds
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
also known as "congenital ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... examination; nonspecific symptoms ... malaise, are common Crigler-Najjar ... Hyperbilirubinemia #Inherited #Congenital ... #bilirubin #hepatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
hemorrhagic rash; symptoms ... organ ischemia -> Congenital ... non-specific viral symptoms ... #Immunization #peds ... #pediatrics #pathophysiology
Causes of Failure to Thrive - Differential Diagnosis Algorithm Adequate Calorie Consumption - Increased Losses:
Failure to Thrive - Differential ... Disease • Liver ... Esophagitis • Congenital ... Algorithm #Causes #Peds ... #Pediatrics
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