26 results
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Diagnosis and Management ... Symptoms and Signs ... : 1. ... Diagnostic Criteria ... #criteria #Tropheryma
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Environmental triggers ... - Postulate 1 ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... : 1. ... glucorticoids if 1)
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... ALS involves: (1) ... : El Escorial criteria ... likelihood of this 1. ... neurology #diagnosis #management
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... mechanism exist): 1) ... Can be triggered ... Crisis #Features #Signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
distribution of nearly 3:1 ... • Lhermitte’s sign ... combination of: 1. ... McDonald diagnostic criteria ... sclerosis #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... • Prevalence: 1- ... associated with DM-1, ... Person Syndrome Pathophysiology ... tendency to fall • Triggers
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... : 1. ... a very common trigger ... Common, early signs