72 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... symptoms, or> 1 ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Environmental triggers ... - Postulate 1 ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Pacemaker Operating Modes
1 - Chamber paced
     A (atrium), V (ventricle), D (dual/both)
2
Operating Modes 1 ... event T - Triggers ... sensed event (A triggered ... depolarization (programmed as ... settings #cardiology #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... : 1. ... glucorticoids if 1)
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... of at least: • 1 ... thrombosis) • 1 ... , presence of 1 ... #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... involves: (1) ... of UMN and LMN signs ... likelihood of this 1. ... neurology #diagnosis #management
Scapholunate Dissociation
The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
bones should be 1- ... "Terry Thomas" sign ... ("Terry Thomas sign ... dislocation • ED Management ... XRay #Diagnosis #Management
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
compromise Clinical Signs ... be present or signs ... Pathophysiology: ... Coli, but can also ... Urine cultures also