7 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Males=Females SIGNS ... TylerLarsenMD #COP ... Pneumonia #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU - Checklist ... esp in work-up/management ... if indicated, also ... summary, and ED triage ... pts a CBC and CMP
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... chlorhexidine as ... re-administration of possible trigger ... Intraoperative #Checklist ... #Diagnosis #Management
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
As soon as ... • If expired CO2 ... reservoir bag and APL ... CardiacArrest #Checklist ... #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
rise is a late sign ... Allocate tasks as ... , invasive BP, CVP ... Intraoperative #Checklist ... #Diagnosis #Management