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diagnosis hematology syndrome admissions admitting challenges checklist comparison cryptogenic differentiation fluid icu leukostasis lysis oncology organizing pearls pneumonia pulmonary responsiveness
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Males=Females SIGNS ... TylerLarsenMD #COP ... Pneumonia #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
cardiac output (CO ... as a surrogate for ... precede other signs ... testing #diagnosis #criticalcare ... comparison #challenges #management
Admitting in the ICU - Checklist VITALS: If bad, stop and go see the patient immediately; you
esp in work-up/management ... if indicated, also ... summary, and ED triage ... pts a CBC and CMP ... diagnosis #workup #criticalcare
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