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diagnosis syndrome hematology neurology oncology amyotrophic differentiation disease lateral leukostasis lysis myeloma person potts sclerosis sps stiff tb tls treatment
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... Summary Clinical ... Signs: • hyperCalcemia ... if FLC value is also
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Summary Epidemiology ... cases Clinical Signs ... decreased reflexes Pathophysiology ... should be done in ALL ... #Summary
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
) Summary ALS: combination ... lateral sclerosis Pathophysiology ... brainstem and multiple ... of UMN and LMN signs ... neurology #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Summary Epidemiology ... Person Syndrome Pathophysiology ... tendency to fall • Triggers ... Parkinson's disease, Multiple
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