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diagnosis syndrome bullous cop cryptogenic dermatology differentiation leukostasis lysis oncology organizing pemphigoid pneumonia polycythemiavera pulmonary pv summary tls treatment tumor
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... erosions in ~20% Management ... #dermatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... present, symptoms, signs ... transformation into AML ... PV #Diagnosis #Management ... Summary #treatment #hematology
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Males=Females SIGNS ... Pneumonia #diagnosis #management
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