51 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Passive neck flexion causes ... While the pathophysiology ... despite severe disease ... #Meningitis #Clinical
Froment’s Test for Ulnar Nerve Palsy

This tests for pinch grip weakness caused by ulnar nerve palsy,
grip weakness caused ... Froment's Sign is ... Jeanne’s sign is ... #Froments #Sign ... #video #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... Environmental triggers ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
Hoffman's sign. ... this specific case ... #Hoffmanns #Sign ... Positive #Abnormal #clinical ... #video #neurology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Chondrodysplasia Neurologic ... #causes #symptoms ... #signs #diagnosis ... #msk
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... further guide management ... orthostatic vital sign ... should be guided by clinical ... the underlying disease