15 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... The underlying pathophysiology ... Can be triggered ... co-existent G6PD deficiency ... Features #Signs #Symptoms
Algorithm for the diagnostic evaluation of dizziness. (HINTS = head-impulse, nystagmus, test of skew.)
Questions regarding the
dizziness) and triggers ... Timing of the symptom ... provoke the symptom ... #Diagnosis #Dizzy ... Dizziness #Algorithm #Differential
TiTrATE schema to approach to Dizziness
 • Time Course: Continuous or Episodic
 • Triggers: Present or
or Episodic • Triggers ... yet imprecise symptom ... TiTrATE #Dizziness #dizzy ... #algorithm #differential ... #diagnosis #neurology
Dizziness and Vertigo Algorithm
Presyncope:
 • Feels "faint" or like they are going to "pass out"
 •
"pass out" • Symptoms ... may be triggered ... Vertigo #Algorithm #dizzy ... #differential # ... diagnosis #neurology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... and iron release Diagnosis ... improvement in symptoms ... #management #cardiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential ... Diagnosis Framework ... Wet beri-beri triggers ... #Diagnosis #syndromes ... beriberi #nutrition #pathophysiology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... • Severe iron deficiency ... #Diagnosis #Pathophysiology ... #causes #cardiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Hypo-Mg2+ • Vitamin deficiency ... overload) Other Symptoms ... • Vitamin D deficiency ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... remainder likely arises ... antibodies) -> Complete deficiency ... immunity Signs/Symptoms ... Agammaglobulinemia #XLinked #pathophysiology