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diagnosis differential algorithm comparison disorders hyperglycemic ketoacidosis ketosis crisis criticalcare diabetic diabeticketoacidosis differentiation dm2 foamed hematology hyperosmolar oncology table treatment
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
) • Diabetic Ketoacidosis ... Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
of re-feeding syndrome ... • Diabetic ketoacidosis ... • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... Hyperosmolar Syndrome ... (HHS) Absolute ... #hhs #pathophysiology ... #comparison #endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
• Urine/serum ketones ... • Urine/serum ketones ... Crisis #Algorithm #management ... #endocrinology ... #Diabetes #DM2 #
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... #management #hematology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
In Starvation Ketosis ... for Refeeding Syndrome ... drips unless also diabetic ... DKA is essentially ... differential #algorithm #management
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