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diagnosis gastroenterology disease gastroesophageal hematology lifestyle syndrome acid algorithm als amyotrophic apml cop cryptogenic differentiation esophageal interventions lateral leukostasis lysis
Diagnosis and Management of Gastroesophageal Reflux Disease (GERD) Definition Presentation Medical Management Extraesophageal Symptoms Long-Term PPI Issues Diagnosis Algorithm Refractory GERD Surgical and Endoscopic
Diagnosis and Management ... Gastroesophageal Reflux ... Disease (GERD) ... Extraesophageal Symptoms ... Gastroesophageal #Reflux
Gastroesophageal Reflux Disease (GERD) - Summary GERD: Diagnosis • Heartburn (substernal burning sensation) and acid regurgitation • Chest pain Extraesophageal
Gastroesophageal Reflux ... Testing Ambulatory reflux ... reduction • Avoid “trigger ... Gastroesophageal #Reflux ... Disease #diagnosis #management
GERD and Recommended Lifestyle Modifications • Avoid fatty meals • Avoid carbonated beverages • Avoid citrus,
GERD and Recommended ... citrus, if it triggers ... symptoms • Eat ... #reflux #acid # ... Modifications #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... Lysis Syndrome: • Pathophysiology ... into serum • Triggers ... TLS #diagnosis #management
Efficacy of lifestyle interventions for GERD Weight loss: - Improvement of GERD symptoms and esophageal pH -
symptoms and esophageal ... esophageal pH and symptoms ... acidity but not symptoms ... symptoms Cessation ... #reflux #management
Esophageal Necrosis Etiology: - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events - Associated
Obstruction with GERD ... injury (by acid reflux ... promote esophageal reflux ... melena - Other GI symptoms ... Necrosis #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... neurology #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Females SIGNS/SYMPTOMS ... misdiagnosed as CAP • Symptoms ... Pneumonia #diagnosis #management
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