13 results
Diagnosis and Management of Gastroesophageal Reflux Disease (GERD)

Definition
Presentation
Medical Management
Extraesophageal Symptoms
Long-Term PPI Issues
Diagnosis Algorithm
Refractory GERD
Surgical and Endoscopic
Diagnosis and Management ... Gastroesophageal Reflux ... Disease (GERD) ... Extraesophageal Symptoms ... Gastroesophageal #Reflux
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Gastroesophageal Reflux ... Testing Ambulatory reflux ... reduction • Avoid “trigger ... Gastroesophageal #Reflux ... Disease #diagnosis #management
GERD and Recommended Lifestyle Modifications
 • Avoid fatty meals
 • Avoid carbonated beverages
 • Avoid citrus,
GERD and Recommended ... citrus, if it triggers ... symptoms • Eat ... #reflux #acid # ... Modifications #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Efficacy of lifestyle interventions for GERD
Weight loss:
 - Improvement of GERD symptoms and esophageal pH
 -
symptoms and esophageal ... esophageal pH and symptoms ... acidity but not symptoms ... symptoms Cessation ... #reflux #management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... Clinical Signs/Symptoms ... erosions in ~20% Management ... #dermatology
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Obstruction with GERD ... injury (by acid reflux ... promote esophageal reflux ... melena - Other GI symptoms ... Necrosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Common Signs and Symptoms ... Pathophysiology ... Approach • Initial management ... #Hematology #HemeOnc