10 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Smoking, Microbial triggers ... female-predominant disease ... of autoimmune disease ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... varies depending on trigger ... or autoimmune disease ... #Treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Primary (Familial ... ▪ Autoimmune diseases ... Common Signs and Symptoms ... Pathophysiology ... #Hematology #HemeOnc
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... assessment+++ Primary ... • Autoimmune diseases ... Adult-onset Still disease ... Lymphohistiocytosis #diagnosis #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... based on symptoms ... causes of liver disease ... including liver and hematologic ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... skin injury) • Neurologic ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
gastrointestinal 4) Primary ... : • Primary pulmonary ... extrapulmonary disease ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... • Elevation of urinary
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... (3) primary lateral ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology ... #diagnosis #management
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... Pruritus with no primary ... pruritus • Hematologic ... Pruritus #Treatment #Algorithm ... #Nephrology #CKD