8 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Disease, PRES Pathophysiology ... #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... lupus erythematosus ... (CNS) dysfunction ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... and CNS • Headache ... : • Symptoms limited ... Chronic B-cell activation
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... skin injury) • Neurologic ... symptoms (headache ... Syndrome #diagnosis #management ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... of the immune system ... Common Signs and Symptoms ... Pathophysiology ... #Hematology #HemeOnc
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Excessive activation ... that results in CNS ... Bilateral signs and/or symptoms ... #neurology #differential
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... cell lymphoma Pathophysiology ... symptoms Histopathological ... TAFRO #diagnosis #management ... #rheumatology #