17 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... of Pregnancy (AFLP ... coagulation defects. 1) HELLP ... most often in 2nd trimester ... #AFLP #obstetrics
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
ICP) • Onset/Trimester ... , no necrosis HELLP ... of Pregnancy (AFLP ... diagnosis #icp #HELLP ... #AFLP
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
coagulation defects. 1) HELLP ... Hemolysis, Elevated Liver ... most often in 2nd trimester ... Pregnancy #TTPHUS #HELLP ... #AFLP #Obstetrics
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Wilsons, Pregnancy - AFLP ... , HELLP • Moderate ... Transaminitis #Algorithm
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... Typically 3rd trimester ... Preeclampsia, HELLP ... iMedEducation #AFLP
Differential Diagnosis of 3rd Trimester Bleeding: #Diagnosis #EM #OBGyn #Third #Trimester #ThirdTrimester #Bleed #Vaginal #Differential #Algorithm
Diagnosis of 3rd Trimester ... Bleeding: #Diagnosis #EM ... #OBGyn #Third #Trimester ... #Differential #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... • Pregnancy: HELLP ... • AST/ALT > ALP ... : Bone, first trimester ... differential #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... - Specific to liver ... - Assists in liver ... : Bone, First trimester
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... , HELLP Moderate ... Differential #Diagnosis #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... - Increased ALP ... disturbance (obstructed liver ... Highest • Bone • Liver ... Differential #Diagnosis #Algorithm