47 results
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
mL/min) of CKD are ... metabolic derangements are ... #Pathophysiology ... #Nephrology #CKD
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
activation 3- DC ... are professional ... phagocytes: Antigen (Ag ... immunity #immunology #pathophysiology
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Promastigotes are ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... activate naive CD4 ... which produce lgE ... Unbound lgE secreted ... #asthma #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
) are produced from ... cell-dependent Ag ... : Ag-presenting ... to CD4+ helper ... Humoral #Immunity #pathophysiology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
occur when the CD4 ... Multiple infections are ... status, and focal neurologic ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
Hyperglycemia and AGE ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
associated with CD4 ... or CD8, depending ... Endogenous antigens are ... ImmuneResponses #immunology #pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
:1 - Bimodal age ... Juvenile: 7 years of age ... Adult: 52 years of age ... regeneration, diffuse CD8 ... PM #Diagnosis #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
ACEI/ARB's are often ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology