23 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... candidate) - Bone ... not required in all
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... mineralization Symptoms ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... DOES NOT OSD in all ... tear (similar symptoms ... #msk
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... Vascular disorders ... the headache (in one ... #differential #diagnosis ... #neurology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... formation MSK ... Nerve Palsies • Disordered ... pathophysiology #diagnosis ... #signs #symptoms
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... Normal: Air > bone ... hearing loss: Bone ... cause unknown) ... Mitochondrial disorders
Characteristics of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
 • Onset: Sudden
 • Intensity: Severe initially, often decreasing
tinnitus (Méniére's disease ... with vascular causes ... Central #Vertigo #diagnosis ... findings #signs #symptoms ... #comparison #neurology
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Framework Symptom ... • Muscular or neurologic ... stroke, Parkinson disease ... Other - ALS, Dementia ... the underlying cause
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential Diagnosis ... Non-compressive Spinal Cord Causes ... Sarcoidosis, Behcet disease ... #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
super-antigen mediated disease ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... MCTD - Bechet disease ... #management #neurology