21 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... ) • Renal disease ... • Anemia 78% (bone ... - Clonal bone marrow
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
POCUS lung exam done ... interstitial lung disease ... partially seen shred sign ... Rt Zone 1. ... #Lung #POCUS #clinical
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Osteonecrosis, bone ... #Diagnosis #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... of bacilli to bone ... CXR should be done
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... Warm AIHA • Bone ... lymphoma • Marginal zone
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... epidemiology of this disease ... 40% of patients diagnosed ... history of the disease ... cells in blood and bone
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
Pathogenesis and Clinical ... to the scaphoid bone ... - Sickle-cell disease ... Hypoxic death of bone ... pathophysiology #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... Shock, Autoimmune disease ... Transplantation including bone ... mean 58 mg/dL in one ... Seizures: Treat with AEDs
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
Paget’s Disease: ... Pathogenesis and Clinical ... CTx - marker of bone ... resorption • Lytic bone ... ALP - marker of bone
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : HLH signs and ... Diagnosis via genetic ... Hemophagocytosis in bone