29 results
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... MSK #diagnosis #signs ... #symptoms #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
clinical findings Abnormal ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Disruption of normal ... osteophyte with normal ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Proximal Weakness, Normal ... Weakness, Incr CK • Bone ... hydroxychloroquine therapy), Normal ... Complications #pathophysiology ... #signs #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology ... of bacilli to bone
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... Areflexia (loss of normal ... leg reflexes) ... Syndrome #MSK #pathophysiology ... #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... movements; also normal ... Motor/Sensory: • Tone ... • Examine for signs ... #PhysicalExam #neurology
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
bladder, urinary reflux ... Enterococcus, Candida) -> Portal ... Signs/Symptoms ... UrinaryTractInfection #LUTI #Pathophysiology ... #Signs #Symptoms