11 results
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... , two, or all three ... transformation to AML ... progression to AML ... Myelodysplastic #Syndromes #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... multiple myeloma, AL ... Significance #hematology #diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... Mucous membranes • Bone ... breath, wasting, anemia ... Psychiatric symptoms ... Loss of teeth Anemia
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
complete paralysis of all ... protein with a normal ... - Of note, normal ... after symptom onset ... the underlying pathophysiology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... loss of muscle, bone ... pseudoanemia is a normal ... of unnecessary diagnostic ... #differential #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms ... products that define normal
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... Etiology: • Pathophysiology ... Neurological symptoms ... circulation: MCA ACA ... Seizures: Treat with AEDs
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Cryoglobulinemic, Hypo/normo-complementemic ... Evans • ITP • Cl-NH ... (-) hemolytic anemia ... Thrombosis in vascular beds-renal ... #Differential #Diagnosis
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings

Parasomnias - Micro-arousal episodes during SWS ->
Intense activation of
• Variable amnesia ... Nightmares #Pediatrics #Peds ... #pathophysiology ... #symptoms #pharmacology ... #diagnosis
Charcot Joint - Neuropathic Arthropathy: Pathogenesis and Clinical findings
 • Impaired joint protection -> abnormal joint
Inflammatory cytokines act ... periarticular bone ... #Arthropathy #pathophysiology ... #diagnosis #signs ... #symptoms