15 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Toxic: Alcohol, Medication ... obstruction, HELLP Syndrome ... GVHD • Toxic: Medication ... #Injury #Differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... vein: Budd-chiari syndrome ... hemolysis) • ALP: Bone ... #injury #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... dechallenge • Acute ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... ) • Liver failure ... tract infection • Medications ... #Kidney #Injury
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... hemolysis) • ALP: Bone ... • Gilbert's syndrome
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for ... ascites removed • Acute ... kidney injury ( ... • Hepatorenal syndrome ... Management #Cirrhosis #treatment
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... • Hepatorenal syndrome ... Treat underlying liver ... → No specific treatment ... #Kidney #Injury
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... regarding need for treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Marrow (Toxic injury ... - Antithyroid medications ... Aplastic Anemia: - Hepatitis ... aplastic anemia Treatment