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differential oncology algorithm management classification clinical hepatology leukemia macrocytic mds monoclonal myelodysplastic physicalexam pulmonary rheumatology signs aafp abnormal acidosis arteritis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... hyperplasia of bone ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology ... GrepMed Recommended Text
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... candidate) - Bone ... #Causes #Workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... bleeding, infections, bone ... cells - Blood and Bone ... • Headaches, bone ... neutropenia) • Bone
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Warm AIHA • Bone ... lymphoma • Marginal zone ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... hypercellular bone ... Anemia • Bone ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Low in bone marrow ... suggests appropriate bone ... #Algorithm #Diagnosis ... #Workup #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
is an adequate bone ... the most likely cause ... recovery also causes ... of the initial work-up ... #Diagnosis #Macrocytosis
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... g/dl LLN B - Bony ... more: • Clonal bone ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... • Bone marrow ... Allogeneic stem cell ... Management #treatment #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... resolve within one ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology #
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