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hematology differential management mds myelodysplastic physicalexam anemia aplastic cancer causes chronic clinical cll dermatology effusions emergencies half hearing knee loss
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... bleeding, infections, bone ... cells - Blood and Bone ... • Headaches, bone ... neutropenia) • Bone
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... • Bone marrow ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Warm AIHA • Bone ... lymphoma • Marginal zone ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... sustained over a one-hour ... shoulder pain, collateral ... #differential #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... the blood and bone ... blood smear • Bone ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... virus (EBV) • Leukemia ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
skin lesions by one ... - Lupus - Leukemia ... cutis Diagnosis ... #diagnosis #dermatology ... #oncology
One and a Half Syndrome on Physical Exam This 28 year old patient presented to clinic with
One and a Half Syndrome ... gaze palsy to one ... result is that one ... the hospital, diagnosed ... #OneAndAHalf #One
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 Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Hematologic - Leukemia ... - Aneurysmal bone ... #differential #diagnosis ... #msk #physicalexam
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
- Differential Diagnosis ... Normal: Air > bone ... hearing loss: Bone ... II ○ Susac’s syndrome ... Noise trauma ○ MS
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