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diagnosis clinical differential physicalexam management neurology rheumatology ophthalmology hepatology dermatology half one oneandahalf workup algorithm liver monoclonal pancytopenia treatment anemia
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... sustained over a one-hour ... shoulder pain, collateral ... : Tumor Lysis Syndrome
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia and Bone ... Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... anemia #diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... • Bone marrow ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Flow cytometry, Bone ... HLH syndrome 5. ... Alcoholism Bone ... • Congenital bone ... Diagnosis #Algorithm #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... as the collar bone ... , breast bone, pelvis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... the blood and bone ... #diagnosis #hematology ... #oncology
Gastric Neuroendocrine Tumor (NET) Types Type 1 - Chronic atrophic gastritis and pernicious anaemia Type 2 - Zollinger
Zollinger Ellison syndrome ... MEN)-1 Type 3 - None ... Classification #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Flow cytometry, Bone ... HLH syndrome 5 ... Alcoholism Bone ... • Congenital bone ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone ... #hematology #diagnosis
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
g/dl LLN B - Bony ... more: • Clonal bone ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
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