27 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... g/dl LLN B - Bony ... more: • Clonal bone ... plasmacytoma, POEMs syndrome ... diagnosis #hematology #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... sustained over a one-hour ... Superior Vena Cava Syndrome ... shoulder pain, collateral ... : Tumor Lysis Syndrome
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
level <3 g/dL • Bone ... g/dL • Clonal bone ... insufficiency, Anemia, and Bone ... disorder • Clonal bone ... hematology #diagnosis #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Splenic Marginal Zone ... Amyloidosis and monoclonal ... TMA • Marginal zone ... Differential #Diagnosis #Oncology
Gastric Neuroendocrine Tumor (NET) Types
Type 1 - Chronic atrophic gastritis and pernicious anaemia
Type 2 - Zollinger
Zollinger Ellison syndrome ... MEN)-1 Type 3 - None ... Classification #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... blood cells in the bone ... blood smear • Bone ... diagnosis #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... • Bone marrow ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone ... Aplastic #Anemia #oncology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
rheumatoid arthritis, monoclonal ... anti-phospholipid syndrome ... , post-bone marrow
Simultagnosia on Physical Exam (Balint Syndrome)

The patient can recognize objects one at a time but cannot
Physical Exam (Balint Syndrome ... recognize objects one ... Simultagnosia #Balint #Syndrome ... PhysicalExam #clinical #video