27 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... predispose to other orthopedic ... • XR, MRI to ... Pain #SickleCell #Disease ... #differential #diagnosis
Midcarpal Instability (MCI) of the Wrist

Intrinsic Midcarpal Instability
Usually affects young, hypermobile patients.
It is due to progressive
performed, the large bone ... subluxating the large bone ... Instability #Wrist #msk #orthopedics ... #clinical #video ... #physicalexam
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone ... #Diagnosis #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... of bacilli to bone ... : - MRI is modality
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... • MRI is more sensitive ... tuberosity Differential diagnosis ... #mri #clinical ... #Radiology #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... Difficulty walking Diagnosis
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... and underlying bone ... #Dislocation #Diagnosis ... symptoms #msk #orthopedics ... #pathophysiology
Extrapulmonary manifestations of sarcoidosis.
a. Endobronchial cobblestones (a nodular appearance of the tracheal wall mucosa). 
b. Diffuse
Perthes—Jüngling disease ... lesions in the hand bones ... MRI scan showing ... manifestations #clinical ... #photo #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Pathogenesis and clinical ... damage weakens the bone ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Pathogenesis and clinical ... tear a portion of bone ... Fractures #msk #diagnosis ... #pathophysiology ... signs #symptoms #orthopedics