14 results
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... and Management ... Summary Clinical ... CT/MRI of the thorax ... patients with bone
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Tuberculosis Diagnosis ... Tuberculin skin test ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Tuberculosis Diagnosis ... Tuberculin skin test ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... - MRI: inflammation ... osteoarticular and skin disease ... #management #Dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... of bacilli to bone ... : - MRI is modality ... CMC_IM #Potts #Disease
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
activation of macrophages ... accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... with excessive macrophage ... age, however the disease ... Hemophagocytosis in bone ... #management #treatment
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... the extent of disease ... muscle wasting Bone ... Inflammation → Macrophage ... enlargement • MRI
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... negative, MOG-IgG test ... MCTD - Bechet disease ... #management #neurology