23 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • XR, MRI to ... • Differentiate ... #differential # ... diagnosis #causes #hematology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
100) • Other manifestations ... Compatible syndrome + MRI ... lymphoproliferative disease ... Lesions #Brain #differential ... causes #radiology #neurology
Extrapulmonary manifestations of sarcoidosis.
a. Endobronchial cobblestones (a nodular appearance of the tracheal wall mucosa). 
b. Diffuse
Extrapulmonary manifestations ... Perthes—Jüngling disease ... lesions in the hand bones ... MRI scan showing ... #clinical #photo
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... - MRI: inflammation ... Osteoarticular manifestations ... osteoarticular and skin disease ... diagnosis #management #Dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... reticularis Differential ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical ... #manifestations ... pathology #lesions #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... manifestation of ... • Hemorrhagic manifestations ... Diagnosis #Management #Hematology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... fragmentation and mild bone ... • MRI is more sensitive ... tibial tuberosity Differential ... #mri #clinical
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
leukoencephalopathy and systemic manifestations ... neuropathy (LHON) plus MRI ... lesions and clinical ... BEE #Syndromes #neurology ... noninflammatory #differential