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diagnosis management hematology hepatology signs syndrome algorithm causes neurology oncology alkaline classification disease disorders liver phosphatase pituitary primary workup abnormal
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... #Elevation #Differential
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... mineralization Symptoms
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... diagnosis #management #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... box indicates all ... ALP, alkaline phosphatase ... Liver #Enzymes #Differential
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... of bacilli to bone ... should be done in ALL
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... Nucleotidase • ALT ... obstruction • ALP ... bile ducts Differential
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
pituitary masses of all ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Classification #pathophysiology ... Diagnosis #NonHodgkin #differential
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