11 results
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... onto lateral hip Signs ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... pain - Frequent fractures
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Dizziness - Vertigo - Differential ... Media • Temporal Bone ... Fracture Central ... symptoms/signs, ... #Differential #
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
, kyphosis and fractures ... • Incr serum ALP ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... and with limb features ... fasciculations Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... middle ear/temporal bone ... pathology) • LP ... Management #Treatment #Neurology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
enzymes (like ALP ... Bowed legs • Fractures ... #Osteomalacia #pathophysiology ... #diagnosis #signs ... #symptoms
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
surgery, trauma, and bone-marrow ... • The cardinal features ... than one after symptom ... the underlying pathophysiology ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... diagnosis #management #neurology ... #differential